Targeted Gene Sequencing
Fast and Accurate DNA Sequencing in Africa
Targeted next-generation sequencing (NGS) allows common and rare genetic variations to be identified rapidly.
Targeted gene sequencing enables the sequencing of specific areas of the genome in a more rapid, comprehensive, and cost-effective manner than whole genome sequencing (WGS).
At KIBs, we use targeted NGS for cancer research and diagnostics, liquid biopsy,
tumor profiling, analysis of circulating tumor cells (CTCs), and minimal residual disease testing. We run a cancer genomics project called CANCEL. To cancel is to neutralize or negate the force or effect of something. If you cancel something you stop it from happening. In a similar manner, CANCEL seeks to stop cancer from happening and to neutralize or negate the effect of cancer. CANCEL uses DNA sequencing, liquid biopsies, bioinformatics, genomics, artificial intelligence (AI), and big data to predict, detect, prevent, and diagnose cancer as well as to improve treatment outcomes in cancer.
More on CANCEL
Services & Applications of Targeted Sequencing
Totogenes leverages on the power of targted NGS to detect and identify genetic conditions that may be affecting your unborn child so that solutions can be found on time to enable your child live a healthy and normal life. Totogenes provides newborn and carrier screening, non-invasive prenatal testing (NIPT) , and preimplantation genetic diagnosis (PGD).
More on TOTOGENESWe also provide custom targeted NGS services to individuals and institutions for the following applications:
Detection and characterization of viruses, bacteria, and other microbes and diagnosis of infectious diseases
Personalized medicine & Pharmacogenomics - to determine how individuals react to drugs and use this knowledge to choose and or design the safest and most effective treatment for the individual
Genomic surveillance - to help identify new or existing genetic variants in viruses and other microbes and this is useful in the analysis, vigilance and control of pathogens such as SARS CoV2
Microbial genetics - to study microbes for purposes of disease control, gene cloning, research, and determination of bacterial drug resistance
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