H. pylori Antigen Test
Synonyms
Campylobacter pylori, Campylobacter From Stomach, Culture-Helicobacter pylori, H pylori Stool Antigen Test
Purpose of The H. pylori Antigen Test
This test detects antigens from the Helicobacter pylori bacteria in stool samples, which aids in diagnosing H. pylori infections, a prevalent cause of peptic ulcers and gastritis. Detecting this infection is critical since persistent H. pylori can cause gastrointestinal irritation and bleeding.
This test can be used with the Fecal Occult Blood Test (FOBT), which looks for blood in the stool that may be concealed and suggests bleeding from ulcers or other gastrointestinal sources when gastrointestinal bleeding is suspected.
Additionally, healthcare providers can conduct the fecal culture test to identify other bacterial infections that might cause similar symptoms, providing further insights into bacterial involvement.
Patient Preparation
About two weeks before the test, the patient should avoid certain medications, such as antibiotics, antacids, bismuth, proton pump inhibitors (PPIs), and H2 blockers.
Samples for H pylori Stool Antigen
2 g (thumbnail size portion of stool)”,” 2 mL liquid stool. Sterile screw-cap vial. Avoid contaminating the samples and keep them Refrigerated.
Reference Range
IgM- 30 – 40 U/mL “,” IgG- 0.75 – 1
Results Turnaround
3 days after receipt of samples.
Diseases / Diagnostic Indicators of H. pylori
Healthcare professionals use the H. pylori stool antigen test to detect infections caused by Helicobacter pylori, which can lead to gastrointestinal diseases like gastritis and duodenal ulcers. High levels of H. pylori antibodies indicate an increased risk of these conditions.
The infection often leads to inflammation of the stomach lining, which can result in chronic gastritis and elevate the risk of peptic ulcer disease. This condition may cause severe abdominal pain, bleeding, and other complications.
Additionally, if left untreated, chronic H. pylori infection can significantly elevate the risk of developing stomach cancer over time. For further information on the effects of H. pylori and associated antibody titers, see this study on H. pylori-related disorders.